리스테린의® 효과를 극대화하기 위해서는 하루 2번, 20ml씩, 30초 동안 사용하는 것이 좋습니다.
그렇다면 30초 동안 입 속에서는 무슨 일이 일어날까요? 왜30초 동안 물고 있어야 하는 것 일까요?
30초 동안 리스테린® 은 박테리아의 세포 표면을 손상시켜 성장을 방해하고 박테리아가 재성장 하는데 걸리는 시간을 지연시킴으로써,1-7 더 많은 박테리아 살균과 더 강력한 플라그 감소 효과를 줍니다. 8*
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*연구설계: 이 실험실 모델에서는, 침에서 나온 생체막이 침으로 코팅된 유리 슬라이드 위에서 배양하였으며, 구강청결제에 노출되기 전에 65시간 동안 배양되었습니다. 살아 있거나/죽은 세포를 정량화 하기 위하여 생체막을 착색시켰습니다.
References: 1. Fine DH, Letizia J, Mandel ID. The effect of rinsing with Listerine antiseptic on the properties of developing dental plaque. J Clin Periodontol. 1985;12:660-666. 2. Ricci-Nittel D, Fourre T. In vivo evaluation of antimicrobial activity of an essential-oil mouthrinse. Presented at: General Session of the International Association for Dental Research: March 16-19, 2011; San Diego, CA. 3. Ross NM, Charles CH, Dills SS. Long-term effects of Listerine antiseptic on dental plaque and gingivitis. J Clin Dent. 1989;1(4):92-95. 4. Drake D, Villhauer AL. An in vitro comparative study determining bactericidal activity of stabilized chlorine dioxide and other oral rinses. J Clin Dent. 2011;22(1):1-5. 5. Andreana S, Nittel-Ricci D, Wu MM, Harper DS, Baxter KA. In vitro antimicrobial activity of vanilla mint Listerine® antiseptic mouthrinse. Presented at: IADR/AADR/CADR 85th General Session and Exhibition. March 2007. 6. Pan PH, Finnegan MB, Sturdivant L, Barnett ML. Comparative antimicrobial activity of an essential oil and an amine fluoride/stannous fluoride mouthrinse in vitro. J Clin Periodontol. 1999;26(7):474-476.7. Kubert D, Rubin M, Barnett ML, Vincent JW. Antiseptic mouthrinse-induced microbial cell surface alterations. Am J Dent. 1993;6(6):277-279. 8. Fine DH, Furgang D, Barnett ML, et al. Effect of an essential oil-containing antiseptic mouthrinse on plaque and salivary Streptococcus mutans levels. J Clin Periodontol. 2000;27(3):157-161.
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